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A phrase used to express satisfaction with the quality of the blackjack hand of another person. Often used to suggest that the player should add another card.

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Download as PDF Printable version. Columbia [2]. Brendan O'Brien [3]. If the patient was receiving warfarin at the time when HIT is diagnosed, the activity of warfarin is reversed with vitamin K.

Various nonheparin agents are used as alternatives to heparin therapy to provide anticoagulation in those with strongly suspected or proven HIT: danaparoid , fondaparinux , bivalirudin , and argatroban.

For instance, argatroban is only recently licensed in the United Kingdom, and danaparoid is not available in the United States.

According to a systematic review , people with HIT treated with lepirudin showed a relative risk reduction of clinical outcome death, amputation, etc.

In addition, people treated with argatroban for HIT showed a relative risk reduction of the above clinical outcomes to be 0. What is known is that women receiving heparin after a recent surgical procedure, particularly cardiothoracic surgery , have a higher risk, while the risk is very low in women just before and after giving birth.

Some studies have shown that HIT is less common in those receiving low molecular weight heparin. While heparin was introduced for clinical use in the late s, new thrombosis in people treated with heparin was not described until , when vascular surgeons reported the association.

Initially, various theories existed about the exact cause of the low platelets in HIT. Gradually, evidence accumulated on the exact underlying mechanism.

Kelton and colleagues at McMaster University Medical School developed the laboratory tests that could be used to confirm or exclude heparin-induced thrombocytopenia.

Treatment was initially limited to aspirin and warfarin, but the s saw the introduction of a number of agents that could provide anticoagulation without a risk of recurrent HIT.

Currently, the term HIT is used without a modifier to describe the immune-mediated severe form. From Wikipedia, the free encyclopedia.

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